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Discovery of new GPCR ligands to illuminate new biology
Although a plurality of drugs target G-protein-coupled receptors (GPCRs), most have emerged from classical medicinal chemistry and pharmacology programs and resemble one another structurally and functionally. Though effective, these drugs are often promiscuous. With the realization that GPCRs signal...
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| Publicado no: | Nat Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835362/ https://ncbi.nlm.nih.gov/pubmed/29045379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2490 |
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