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Discovery of new GPCR ligands to illuminate new biology
Although a plurality of drugs target G-protein-coupled receptors (GPCRs), most have emerged from classical medicinal chemistry and pharmacology programs and resemble one another structurally and functionally. Though effective, these drugs are often promiscuous. With the realization that GPCRs signal...
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| Gepubliceerd in: | Nat Chem Biol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835362/ https://ncbi.nlm.nih.gov/pubmed/29045379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2490 |
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