A carregar...

Ligand Discovery from a Dopamine D(3) Receptor Homology Model and Crystal Structure

G-Protein coupled receptors (GPCRs) are intensely studied as drug targets and for their role in signaling. With the determination of the first crystal structures, interest in structure-based ligand discovery has increased. Unfortunately, most GPCRs lack experimental structures. The determination of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Carlsson, Jens, Coleman, Ryan G., Setola, Vincent, Irwin, John J., Fan, Hao, Schlessinger, Avner, Sali, Andrej, Roth, Bryan L., Shoichet, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197762/
https://ncbi.nlm.nih.gov/pubmed/21926995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.662
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!