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Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1
The Large-neutral Amino Acid Transporter 1 (LAT-1)—a sodium-independent exchanger of amino acids, thyroid hormones, and prescription drugs—is highly expressed in the blood–brain barrier and various types of cancer. LAT-1 plays an important role in cancer development as well as in mediating drug and...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619328/ https://ncbi.nlm.nih.gov/pubmed/23509259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218165110 |
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