Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation

Histone post-translational modifications regulate chromatin structure and function largely through interactions with effector proteins that often contain multiple histone-binding domains. While significant progress has been made characterizing individual effector domains, the role of paired domains...

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Главные авторы: Rothbart, Scott B., Dickson, Bradley M., Ong, Michelle S., Krajewski, Krzysztof, Houliston, Scott, Kireev, Dmitri B., Arrowsmith, Cheryl H., Strahl, Brian D.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2013
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690401/
https://ncbi.nlm.nih.gov/pubmed/23752590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.220467.113
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