Association of UHRF1 with H3K9 methylation directs the maintenance of DNA methylation

A fundamental challenge in mammalian biology has been elucidating mechanisms linking DNA methylation and histone post-translational modifications. Human UHRF1 (ubiquitin-like, PHD and RING finger containing 1) has multiple domains that bind chromatin and is implicated genetically in DNA methylation...

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Detalhes bibliográficos
Main Authors: Rothbart, Scott B., Krajewski, Krzysztof, Nady, Nataliya, Tempel, Wolfram, Xue, Sheng, Badeaux, Aimee I., Barsyte-Lovejoy, Dalia, Martinez, Jorge Y., Bedford, Mark T., Fuchs, Stephen M., Arrowsmith, Cheryl H., Strahl, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492551/
https://ncbi.nlm.nih.gov/pubmed/23022729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2391
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