Structural plasticity of methyllysine recognition by the tandem Tudor domain of 53BP1

p53 is dynamically regulated through various posttranslational modifications (PTMs), which differentially modulate its function and stability. The dimethylated marks p53K370me2 and p53K382me2 are associated with p53 activation or stabilization and both are recognized by the tandem Tudor domain (TTD)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Structure
Egile Nagusiak: Tong, Qiong, Cui, Gaofeng, Botuyan, Maria Victoria, Rothbart, Scott B., Hayashi, Ryo, Musselman, Catherine A., Singh, Namit, Appella, Ettore, Strahl, Brian D., Mer, Georges, Kutateladze, Tatiana G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321732/
https://ncbi.nlm.nih.gov/pubmed/25579814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.11.013
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