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Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR
P53-binding protein 1 (53BP1) regulates the double-strand break (DSB) repair pathway choice. A recently identified 53BP1-binding protein Tudor-interacting repair regulator (TIRR) modulates the access of 53BP1 to DSBs by masking the H4K20me2 binding surface on 53BP1, but the underlying mechanism rema...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5974088/ https://ncbi.nlm.nih.gov/pubmed/29844495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04557-2 |
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