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An Oligomerized 53BP1 Tudor Domain Suffices for Recognition of DNA Double-Strand Breaks
53BP1, the vertebrate ortholog of the budding yeast Rad9 and fission yeast Crb2/Rhp9 checkpoint proteins, is recruited rapidly to sites of DNA double-strand breaks (DSBs). A tandem tudor domain in human 53BP1 that recognizes methylated residues in the histone core is necessary, but not sufficient, f...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643802/ https://ncbi.nlm.nih.gov/pubmed/19064641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01011-08 |
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