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Expression of Ror2 Mediates Invasive Phenotypes in Renal Cell Carcinoma

Ror2 is a Wnt ligand receptor that is overexpressed in a variety of tumors including clear cell renal cell carcinoma (ccRCC). Here we demonstrate that expression of wild type Ror2 results in increased tumorigenic properties in in vitro cell culture and in vivo xenograft models. In addition, Ror2 exp...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rasmussen, Neal R., Debebe, Zufan, Wright, Tricia M., Brooks, Samira A., Sendor, Adam B., Brannon, A . Rose, Hakimi, A . Ari, Hsieh, James J., Choueiri, Toni K., Tamboli, Pheroze, Maranchie, Jodi K., Hinds, Peter, Wallen, Eric M., Simpson, Catherine, Norris, Jacqueline L., Janzen, William P., Rathmell, W. Kimryn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277431/
https://ncbi.nlm.nih.gov/pubmed/25542006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116101
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