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Biophysical probes reveal a “compromise” nature of the methyllysine binding pocket in L3MBTL1

Histone lysine methylation (Kme) encodes essential information modulating many biological processes including gene expression and transcriptional regulation. However, the atomic-level recognition mechanisms of methylated histones by their respective adaptor proteins are still elusive. For instance,...

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Bibliografiska uppgifter
Huvudupphovsmän: Gao, Cen, Herold, J. Martin, Kireev, Dmitri, Wigle, Tim, Norris, Jacqueline L., Frye, Stephen
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082497/
https://ncbi.nlm.nih.gov/pubmed/21428286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja110432e
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