The landscape of kinase fusions in cancer

by Stransky, Nicolas, Cerami, Ethan, Schalm, Stefanie, Kim, Joseph L., Lengauer, Christoph
Published 2014

Targeting cancer with kinase inhibitors

by Gross, Stefan, Rahal, Rami, Stransky, Nicolas, Lengauer, Christoph, Hoeflich, Klaus P.
Published in J Clin Invest (2015)

Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods

by Haas, Brian J., Dobin, Alexander, Li, Bo, Stransky, Nicolas, Pochet, Nathalie, Regev, Aviv
Published in Genome Biol (2019)

Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer

by Dutt, Amit, Ramos, Alex H., Hammerman, Peter S., Mermel, Craig, Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S., Meyerson, Matthew
Published 2011

A Novel Epigenetic Phenotype Associated With the Most Aggressive Pathway of Bladder Tumor Progression

by Vallot, Céline, Stransky, Nicolas, Bernard-Pierrot, Isabelle, Hérault, Aurélie, Zucman-Rossi, Jessica, Chapeaublanc, Elodie, Vordos, Dimitri, Laplanche, Agnès, Benhamou, Simone, Lebret, Thierry, Southgate, Jennifer, Allory, Yves, Radvanyi, François
Published 2011

A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein

by Pop, Marius S, Stransky, Nicolas, Garvie, Colin W, Theurillat, Jean-Philippe, Lewis, Timothy A, Zhong, Cheng, Culyba, Elizabeth K, Lin, Fallon, Daniels, Douglas S, Pagliarini, Raymond, Ronco, Lucienne, Koehler, Angela N, Garraway, Levi A
Published 2014

Nuclear factor I/B is an oncogene in small cell lung cancer

by Dooley, Alison L., Winslow, Monte M., Chiang, Derek Y., Banerji, Shantanu, Stransky, Nicolas, Dayton, Talya L., Snyder, Eric L., Senna, Stephanie, Whittaker, Charles A., Bronson, Roderick T., Crowley, Denise, Barretina, Jordi, Garraway, Levi, Meyerson, Matthew, Jacks, Tyler
Published 2011

Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes

by Jones, Siân, Stransky, Nicolas, McCord, Christine L., Cerami, Ethan, Lagowski, James, Kelly, Devon, Angiuoli, Samuel V., Sausen, Mark, Kann, Lisa, Shukla, Manish, Makar, Rosemary, Wood, Laura D., Diaz, Luis A., Lengauer, Christoph, Velculescu, Victor E.
Published in Nat Commun (2014)

TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer

by Dufour, Florent, Silina, Linda, Neyret-Kahn, Hélène, Moreno-Vega, Aura, Krucker, Clémentine, Karboul, Narjesse, Dorland-Galliot, Marion, Maillé, Pascale, Chapeaublanc, Elodie, Allory, Yves, Stransky, Nicolas, Haegel, Hélène, Menguy, Thierry, Duong, Vanessa, Radvanyi, François, Bernard-Pierrot, Isabelle
Published in Br J Cancer (2019)

ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens

by Shao, Diane D., Tsherniak, Aviad, Gopal, Shuba, Weir, Barbara A., Tamayo, Pablo, Stransky, Nicolas, Schumacher, Steven E., Zack, Travis I., Beroukhim, Rameen, Garraway, Levi A., Margolin, Adam A., Root, David E., Hahn, William C., Mesirov, Jill P.
Published 2013

Consistency of drug profiles and predictors in large-scale cancer cell line data

by Stransky, Nicolas, Ghandi, Mahmoud, Kryukov, Gregory V., Garraway, Levi A., Amzallag, Arnaud, Pruteanu-Malinici, Iulian, Haber, Daniel A., Ramaswamy, Sridhar, Benes, Cyril H., Lehár, Joseph, Liu, Manway, Sonkin, Dmitriy, Kauffmann, Audrey, Venkatesan, Kavitha, Edelman, Elena J., Riester, Markus, Barretina, Jordi, Caponigro, Giordano, Schlegel, Robert, Sellers, William, Stegmeier, Frank, Morrissey, Michael, Menden, Michael P., Iorio, Francesco, Stratton, Michael R., McDermott, Ultan, Saez-Rodriguez, Julio, Garnett, Mathew J.
Published in Nature (2015)

Genomic Correlate of Exceptional Erlotinib Response in Head and Neck Squamous Cell Carcinoma

by Van Allen, Eliezer M., Lui, Vivian W. Y., Egloff, Ann Marie, Goetz, Eva M., Li, Hua, Johnson, Jonas T., Duvvuri, Umamaheswar, Bauman, Julie E., Stransky, Nicolas, Zeng, Yan, Gilbert, Breean R., Pendleton, Kelsey P., Wang, Lin, Chiosea, Simion, Sougnez, Carrie, Wagle, Nikhil, Zhang, Fan, Du, Yu, Close, David, Johnston, Paul A., McKenna, Aaron, Carter, Scott L., Golub, Todd R., Getz, Gad, Mills, Gordon B., Garraway, Levi A., Grandis, Jennifer R.
Published in JAMA Oncol (2015)

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

by Cheung, Hiu Wing, Cowley, Glenn S., Weir, Barbara A., Boehm, Jesse S., Rusin, Scott, Scott, Justine A., East, Alexandra, Ali, Levi D., Lizotte, Patrick H., Wong, Terence C., Jiang, Guozhi, Hsiao, Jessica, Mermel, Craig H., Getz, Gad, Barretina, Jordi, Gopal, Shuba, Tamayo, Pablo, Gould, Joshua, Tsherniak, Aviad, Stransky, Nicolas, Luo, Biao, Ren, Yin, Drapkin, Ronny, Bhatia, Sangeeta N., Mesirov, Jill P., Garraway, Levi A., Meyerson, Matthew, Lander, Eric S., Root, David E., Hahn, William C.
Published 2011

Functional genomics reveals serine synthesis is essential in PHGDH-amplified breast cancer

by Possemato, Richard, Marks, Kevin M., Shaul, Yoav D., Pacold, Michael E., Kim, Dohoon, Birsoy, Kivanç, Sethumadhavan, Shalini, Woo, Hin-Koon, Jang, Hyun G., Jha, Abhishek K., Chen, Walter W., Barrett, Francesca G., Stransky, Nicolas, Tsun, Zhi-Yang, Cowley, Glenn S., Barretina, Jordi, Kalaany, Nada Y., Hsu, Peggy P., Ottina, Kathleen, Chan, Albert M., Yuan, Bingbing, Garraway, Levi A., Root, David E., Mino-Kenudson, Mari, Brachtel, Elena F., Driggers, Edward M., Sabatini, David M.
Published 2011

An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules

by Basu, Amrita, Bodycombe, Nicole E., Cheah, Jaime H., Price, Edmund V., Liu, Ke, Schaefer, Giannina I., Ebright, Richard Y., Stewart, Michelle L., Ito, Daisuke, Wang, Stephanie, Bracha, Abigail L., Liefeld, Ted, Wawer, Mathias, Gilbert, Joshua C., Wilson, Andrew J., Stransky, Nicolas, Kryukov, Gregory V., Dancik, Vlado, Barretina, Jordi, Garraway, Levi A., Hon, C. Suk-Yee, Munoz, Benito, Bittker, Joshua A., Stockwell, Brent R., Khabele, Dineo, Stern, Andrew M., Clemons, Paul A., Shamji, Alykhan F., Schreiber, Stuart L.
Published 2013

COT/MAP3K8 drives resistance to RAF inhibition through MAP kinase pathway reactivation

by Johannessen, Cory M., Boehm, Jesse S., Kim, So Young, Thomas, Sapana R., Wardwell, Leslie, Johnson, Laura A., Emery, Caroline M., Stransky, Nicolas, Cogdill, Alexandria P., Barretina, Jordi, Caponigro, Giordano, Hieronymus, Haley, Murray, Ryan R., Salehi-Ashtiani, Kourosh, Hill, David E., Vidal, Marc, Zhao, Jean J., Yang, Xiaoping, Alkan, Ozan, Kim, Sungjoon, Harris, Jennifer L., Wilson, Christopher J., Myer, Vic E., Finan, Peter M., Root, David E., Roberts, Thomas M., Golub, Todd, Flaherty, Keith T., Dummer, Reinhard, Weber, Barbara, Sellers, William R., Schlegel, Robert, Wargo, Jennifer A., Hahn, William C., Garraway, Levi A.
Published 2010

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

by Lohr, Jens G., Stojanov, Petar, Lawrence, Michael S., Auclair, Daniel, Chapuy, Bjoern, Sougnez, Carrie, Cruz-Gordillo, Peter, Knoechel, Birgit, Asmann, Yan W., Slager, Susan L., Novak, Anne J., Dogan, Ahmet, Ansell, Stephen M., Link, Brian K., Zou, Lihua, Gould, Joshua, Saksena, Gordon, Stransky, Nicolas, Rangel-Escareño, Claudia, Fernandez-Lopez, Juan Carlos, Hidalgo-Miranda, Alfredo, Melendez-Zajgla, Jorge, Hernández-Lemus, Enrique, Schwarz-Cruz y Celis, Angela, Imaz-Rosshandler, Ivan, Ojesina, Akinyemi I., Jung, Joonil, Pedamallu, Chandra S., Lander, Eric S., Habermann, Thomas M., Cerhan, James R., Shipp, Margaret A., Getz, Gad, Golub, Todd R.
Published 2012

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

by Bass, Adam J, Lawrence, Michael S, Brace, Lear E, Ramos, Alex H, Drier, Yotam, Cibulskis, Kristian, Sougnez, Carrie, Voet, Douglas, Saksena, Gordon, Sivachenko, Andrey, Jing, Rui, Parkin, Melissa, Pugh, Trevor, Verhaak, Roel G, Stransky, Nicolas, Boutin, Adam T, Barretina, Jordi, Solit, David B, Vakiani, Evi, Shao, Wenlin, Mishina, Yuji, Warmuth, Markus, Jimenez, Jose, Chiang, Derek Y, Signoretti, Sabina, Kaelin, William G, Spardy, Nicole, Hahn, William C, Hoshida, Yujin, Ogino, Shuji, DePinho, Ronald A, Chin, Lynda, Garraway, Levi A, Fuchs, Charles S, Baselga, Jose, Tabernero, Josep, Gabriel, Stacey, Lander, Eric S, Getz, Gad, Meyerson, Matthew
Published 2011

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

by Stransky, Nicolas, Egloff, Ann Marie, Tward, Aaron D., Kostic, Aleksandar D., Cibulskis, Kristian, Sivachenko, Andrey, Kryukov, Gregory V., Lawrence, Michael, Sougnez, Carrie, McKenna, Aaron, Shefler, Erica, Ramos, Alex H., Stojanov, Petar, Carter, Scott L., Voet, Douglas, Cortés, Maria L, Auclair, Daniel, Berger, Michael F., Saksena, Gordon, Guiducci, Candace, Onofrio, Robert, Parkin, Melissa, Romkes, Marjorie, Weissfeld, Joel L., Seethala, Raja R., Wang, Lin, Rangel-Escareño, Claudia, Fernandez-Lopez, Juan Carlos, Hidalgo-Miranda, Alfredo, Melendez-Zajgla, Jorge, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Meyerson, Matthew, Lander, Eric S., Getz, Gad, Golub, Todd R., Garraway, Levi A., Grandis, Jennifer R.
Published 2011

A Landscape of Driver Mutations in Melanoma

by Hodis, Eran, Watson, Ian R., Kryukov, Gregory V., Arold, Stefan T., Imielinski, Marcin, Theurillat, Jean-Philippe, Nickerson, Elizabeth, Auclair, Daniel, Li, Liren, Place, Chelsea, DiCara, Daniel, Ramos, Alex H., Lawrence, Michael S., Cibulskis, Kristian, Sivachenko, Andrey, Voet, Douglas, Saksena, Gordon, Stransky, Nicolas, Onofrio, Robert C., Winckler, Wendy, Ardlie, Kristin, Wagle, Nikhil, Wargo, Jennifer, Chong, Kelly, Morton, Donald L., Stemke-Hale, Katherine, Chen, Guo, Noble, Michael, Meyerson, Matthew, Ladbury, John E., Davies, Michael A., Gershenwald, Jeffrey E., Wagner, Stephan N., Hoon, Dave S.B., Schadendorf, Dirk, Lander, Eric S., Gabriel, Stacey B., Getz, Gad, Garraway, Levi A., Chin, Lynda
Published 2012