Drug susceptibility prediction against a panel of drugs using kernelized Bayesian multitask learning

af Gönen, Mehmet, Margolin, Adam A.
Udgivet 2014

Simulation Studies as Designed Experiments: The Comparison of Penalized Regression Models in the “Large p, Small n” Setting

af Chaibub Neto, Elias, Bare, J. Christopher, Margolin, Adam A.
Udgivet 2014

STEPWISE GROUP SPARSE REGRESSION (SGSR): GENE-SET-BASED PHARMACOGENOMIC PREDICTIVE MODELS WITH STEPWISE SELECTION OF FUNCTIONAL PRIORS()

af JANG, IN SOCK, DIENSTMANN, RODRIGO, MARGOLIN, ADAM A., GUINNEY, JUSTIN
Udgivet i Pac Symp Biocomput (2015)

The Stream Algorithm: Computationally Efficient Ridge-Regression via Bayesian Model Averaging, and Applications to Pharmacogenomic Prediction of Cancer Cell Line Sensitivity

af Neto, Elias Chaibub, Jang, In Sock, Friend, Stephen H., Margolin, Adam A.
Udgivet 2014

Modeling gene-wise dependencies improves the identification of drug response biomarkers in cancer studies

af Nikolova, Olga, Moser, Russell, Kemp, Christopher, Gönen, Mehmet, Margolin, Adam A
Udgivet i Bioinformatics (2017)

ChIP-on-chip significance analysis reveals ubiquitous transcription factor binding

af Margolin, Adam A, Palomero, Teresa, Ferrando, Adolfo A, Califano, Andrea, Stolovitzky, Gustavo
Udgivet i BMC Bioinformatics (2007)

SHIFT: speedy histopathological-to-immunofluorescent translation of whole slide images using conditional generative adversarial networks

af Burlingame, Erik A., Margolin, Adam A., Gray, Joe W., Chang, Young Hwan
Udgivet i Proc SPIE Int Soc Opt Eng (2018)

SYSTEMATIC ASSESSMENT OF ANALYTICAL METHODS FOR DRUG SENSITIVITY PREDICTION FROM CANCER CELL LINE DATA

af Jang, In Sock, Neto, Elias Chaibub, Guinney, Justin, Friend, Stephen H., Margolin, Adam A.
Udgivet 2014

Toward better benchmarking: challenge-based methods assessment in cancer genomics

af Boutros, Paul C, Margolin, Adam A, Stuart, Joshua M, Califano, Andrea, Stolovitzky, Gustavo
Udgivet i Genome Biol (2014)

ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes

af Margolin, Adam A., Palomero, Teresa, Sumazin, Pavel, Califano, Andrea, Ferrando, Adolfo A., Stolovitzky, Gustavo
Udgivet 2009

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

af Margolin, Adam A, Nemenman, Ilya, Basso, Katia, Wiggins, Chris, Stolovitzky, Gustavo, Favera, Riccardo Dalla, Califano, Andrea
Udgivet 2006

Empirical Bayes Analysis of Quantitative Proteomics Experiments

af Margolin, Adam A., Ong, Shao-En, Schenone, Monica, Gould, Robert, Schreiber, Stuart L., Carr, Steven A., Golub, Todd R.
Udgivet 2009

Chemical Genomics Identifies Small-Molecule MCL1 Repressors and BCL-xL as a Predictor of MCL1 Dependency

af Wei, Guo, Margolin, Adam A., Haery, Leila, Brown, Emily, Cucolo, Lisa, Julian, Bina, Shehata, Shyemaa, Kung, Andrew L., Beroukhim, Rameen, Golub, Todd R.
Udgivet 2012

Enabling transparent and collaborative computational analysis of 12 tumor types within The Cancer Genome Atlas

af Omberg, Larsson, Ellrott, Kyle, Yuan, Yuan, Kandoth, Cyriac, Wong, Chris, Kellen, Michael R, Friend, Stephen H, Stuart, Josh, Liang, Han, Margolin, Adam A
Udgivet 2013

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells

af Basso, Katia, Saito, Masumichi, Sumazin, Pavel, Margolin, Adam A., Wang, Kai, Lim, Wei-Keat, Kitagawa, Yukiko, Schneider, Christof, Alvarez, Mariano J., Califano, Andrea, Dalla-Favera, Riccardo
Udgivet 2010

Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy

af Medler, Terry R., Murugan, Dhaarini, Horton, Wesley, Kumar, Sushil, Cotechini, Tiziana, Forsyth, Alexandra M., Leyshock, Patrick, Leitenberger, Justin J., Kulesz-Martin, Molly, Margolin, Adam A., Werb, Zena, Coussens, Lisa M.
Udgivet i Cancer Cell (2018)

Genome-wide Identification of Post-translational Modulators of Transcription Factor Activity in Human B-Cells

af Wang, Kai, Saito, Masumichi, Bisikirska, Brygida C., Alvarez, Mariano J., Lim, Wei Keat, Rajbhandari, Presha, Shen, Qiong, Nemenman, Ilya, Basso, Katia, Margolin, Adam A., Klein, Ulf, Dalla-Favera, Riccardo, Califano, Andrea
Udgivet 2009

Germline contamination and leakage in whole genome somatic single nucleotide variant detection

af Sendorek, Dorota H., Caloian, Cristian, Ellrott, Kyle, Bare, J. Christopher, Yamaguchi, Takafumi N., Ewing, Adam D., Houlahan, Kathleen E., Norman, Thea C., Margolin, Adam A., Stuart, Joshua M., Boutros, Paul C.
Udgivet i BMC Bioinformatics (2018)

Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism

af Davis, Ryan J., Gönen, Mehmet, Margineantu, Daciana H., Handeli, Shlomo, Swanger, Jherek, Hoellerbauer, Pia, Paddison, Patrick J., Gu, Haiwei, Raftery, Daniel, Grim, Jonathan E., Hockenbery, David M., Margolin, Adam A., Clurman, Bruce E.
Udgivet i Proc Natl Acad Sci U S A (2018)

Functional kinomics identifies candidate therapeutic targets in head and neck cancer

af Moser, Russell, Xu, Chang, Kao, Michael, Annis, James, Lerma, Luisa Angelica, Schaupp, Christopher M., Gurley, Kay E., Jang, In Sock, Biktasova, Asel, Yarbrough, Wendell G., Margolin, Adam A., Grandori, Carla, Kemp, Christopher J., Méndez, Eduardo
Udgivet 2014