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STEPWISE GROUP SPARSE REGRESSION (SGSR): GENE-SET-BASED PHARMACOGENOMIC PREDICTIVE MODELS WITH STEPWISE SELECTION OF FUNCTIONAL PRIORS()

Complex mechanisms involving genomic aberrations in numerous proteins and pathways are believed to be a key cause of many diseases such as cancer. With recent advances in genomics, elucidating the molecular basis of cancer at a patient level is now feasible, and has led to personalized treatment str...

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Bibliografske podrobnosti
izdano v:Pac Symp Biocomput
Main Authors: JANG, IN SOCK, DIENSTMANN, RODRIGO, MARGOLIN, ADAM A., GUINNEY, JUSTIN
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299910/
https://ncbi.nlm.nih.gov/pubmed/25592566
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