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Prospective: Database of genomic biomarkers for cancer drugs and clinical targetability in solid tumors

Comprehensive genomic profiling is expected to revolutionize cancer therapy. In this Prospective, we present the prevalence of mutations and copy number alterations with predictive associations across solid tumors at different levels of stringency for gene-drug targetability. More than 90% of TCGA s...

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Détails bibliographiques
Publié dans:Cancer Discov
Auteurs principaux: Dienstmann, Rodrigo, Jang, In Sock, Bot, Brian, Friend, Stephen, Guinney, Justin
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825796/
https://ncbi.nlm.nih.gov/pubmed/25656898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-1118
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