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Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors
The fibroblast growth factor receptor (FGFR) cascade plays crucial roles in tumor cell proliferation, angiogenesis, migration and survival. Accumulating evidence suggests that in some tumor types, FGFRs are bona fide oncogenes to which cancer cells are addicted. Because FGFR inhibition can reduce pr...
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| Publicado no: | Ann Oncol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433501/ https://ncbi.nlm.nih.gov/pubmed/24265351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdt419 |
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