Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells

BCL6 is a transcriptional repressor required for mature B-cell germinal center (GC) formation and implicated in lymphomagenesis. BCL6's physiologic function is only partially known because the complete set of its targets in GC B cells has not been identified. To address this issue, we used an i...

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Autori principali: Basso, Katia, Saito, Masumichi, Sumazin, Pavel, Margolin, Adam A., Wang, Kai, Lim, Wei-Keat, Kitagawa, Yukiko, Schneider, Christof, Alvarez, Mariano J., Califano, Andrea, Dalla-Favera, Riccardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Immunobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817639/
https://ncbi.nlm.nih.gov/pubmed/19965633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-227017
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