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A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers

Assembly of a transcriptional and post-translational molecular interaction network in B cells, the human B-cell interactome (HBCI), reveals a hierarchical, transcriptional control module, where MYB and FOXM1 act as synergistic master regulators of proliferation in the germinal center (GC). Eighty pe...

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Detalhes bibliográficos
Main Authors: Lefebvre, Celine, Rajbhandari, Presha, Alvarez, Mariano J, Bandaru, Pradeep, Lim, Wei Keat, Sato, Mai, Wang, Kai, Sumazin, Pavel, Kustagi, Manjunath, Bisikirska, Brygida C, Basso, Katia, Beltrao, Pedro, Krogan, Nevan, Gautier, Jean, Dalla-Favera, Riccardo, Califano, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913282/
https://ncbi.nlm.nih.gov/pubmed/20531406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.31
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