BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma

The BCL6 proto-oncogene encodes a transcriptional repressor that is required for germinal center (GC) formation and whose deregulation by genomic lesions is implicated in the pathogenesis of GC-derived diffuse large B cell lymphoma (DLBCL) and, less frequently, follicular lymphoma (FL). The biologic...

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Detalhes bibliográficos
Main Authors: Saito, Masumichi, Novak, Urban, Piovan, Erich, Basso, Katia, Sumazin, Pavel, Schneider, Christof, Crespo, Marta, Shen, Qiong, Bhagat, Govind, Califano, Andrea, Chadburn, Amy, Pasqualucci, Laura, Dalla-Favera, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708681/
https://ncbi.nlm.nih.gov/pubmed/19549844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903854106
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