ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

BACKGROUND: Elucidating gene regulatory networks is crucial for understanding normal cell physiology and complex pathologic phenotypes. Existing computational methods for the genome-wide "reverse engineering" of such networks have been successful only for lower eukaryotes with simple genom...

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Huvudupphovsmän: Margolin, Adam A, Nemenman, Ilya, Basso, Katia, Wiggins, Chris, Stolovitzky, Gustavo, Favera, Riccardo Dalla, Califano, Andrea
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2006
Ämnen:
Proceedings
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810318/
https://ncbi.nlm.nih.gov/pubmed/16723010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-S1-S7
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