Relieving Autophagy and 4EBP1 from Rapamycin Resistance

od Nyfeler, Beat, Bergman, Philip, Triantafellow, Ellen, Wilson, Christopher J., Zhu, Yanyi, Radetich, Branko, Finan, Peter M., Klionsky, Daniel J., Murphy, Leon O.
Izdano 2011

TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1

od Dibble, Christian C., Elis, Winfried, Menon, Suchithra, Qin, Wei, Klekota, Justin, Asara, John M., Finan, Peter M., Kwiatkowski, David J., Murphy, Leon O., Manning, Brendan D.
Izdano 2012

RAD001 Enhances the Potency of BEZ235 to Inhibit mTOR Signaling and Tumor Growth

od Nyfeler, Beat, Chen, Yan, Li, Xiaoyan, Pinzon-Ortiz, Maria, Wang, Zuncai, Reddy, Anupama, Pradhan, Elina, Das, Rita, Lehár, Joseph, Schlegel, Robert, Finan, Peter M., Cao, Z. Alexander, Murphy, Leon O., Huang, Alan
Izdano 2012

Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo

od Honda, Ayako, Harrington, Edmund, Cornella-Taracido, Ivan, Furet, Pascal, Knapp, Mark S., Glick, Meir, Triantafellow, Ellen, Dowdle, William E., Wiedershain, Dmitri, Maniara, Wieslawa, Moore, Christine, Finan, Peter M., Hamann, Lawrence G., Firestone, Brant, Murphy, Leon O., Keaney, Erin P.
Izdano u ACS Med Chem Lett (2015)

Defective Autophagy and mTORC1 Signaling in Myotubularin Null Mice

od Fetalvero, Kristina M., Yu, Yenyen, Goetschkes, Margaret, Liang, Guiqing, Valdez, Reginald A., Gould, Ty, Triantafellow, Ellen, Bergling, Sebastian, Loureiro, Joseph, Eash, John, Lin, Victor, Porter, Jeffrey A., Finan, Peter M., Walsh, Kenneth, Yang, Yi, Mao, Xiaohong, Murphy, Leon O.
Izdano 2013

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

od Düvel, Katrin, Yecies, Jessica L., Menon, Suchithra, Raman, Pichai, Lipovsky, Alex I., Souza, Amanda L., Triantafellow, Ellen, Ma, Qicheng, Gorski, Regina, Cleaver, Stephen, Heiden, Matthew G. Vander, MacKeigan, Jeffrey P., Finan, Peter M., Clish, Clary B., Murphy, Leon O., Manning, Brendan D.
Izdano 2010

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

od Nicklin, Paul, Bergman, Philip, Zhang, Bailin, Triantafellow, Ellen, Wang, Henry, Nyfeler, Beat, Yang, Haidi, Hild, Marc, Kung, Charles, Wilson, Christopher, Myer, Vic E., MacKeigan, Jeffrey P., Porter, Jeffrey A., Wang, Y. Karen, Cantley, Lewis C., Finan, Peter M., Murphy, Leon O.
Izdano 2009

PIKfyve, a class III PI-kinase, is the target of the small molecular IL12/23 inhibitor apilimod and a new player in toll-like receptor signaling

od Cai, Xinming, Xu, Yongyao, Cheung, Atwood K., Tomlinson, Ronald C., Alcázar-Román, Abel, Murphy, Leon, Billich, Andreas, Zhang, Bailin, Feng, Yan, Klumpp, Martin, Rondeau, Jean-Michel, Fazal, Aleem N., Wilson, Christopher J., Myer, Vic, Joberty, Gerard, Bouwmeester, Tewis, Labow, Mark A., Finan, Peter M., Porter, Jeffrey A., Ploegh, Hidde L., Baird, Daniel, De Camilli, Pietro, Tallarico, John A., Huang, Qian
Izdano u Chem Biol (2013)

Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies

od Ettenberg, Seth A., Charlat, Olga, Daley, Michael P., Liu, Shanming, Vincent, Karen J., Stuart, Darrin D., Schuller, Alwin G., Yuan, Jing, Ospina, Beatriz, Green, John, Yu, Qunyan, Walsh, Renee, Li, Sharon, Schmitz, Rita, Heine, Holger, Bilic, Sanela, Ostrom, Lance, Mosher, Rebecca, Hartlepp, K. Felix, Zhu, Zhenping, Fawell, Stephen, Yao, Yung-Mae, Stover, David, Finan, Peter M., Porter, Jeffery A., Sellers, William R., Klagge, Ingo M., Cong, Feng
Izdano 2010

COT/MAP3K8 drives resistance to RAF inhibition through MAP kinase pathway reactivation

od Johannessen, Cory M., Boehm, Jesse S., Kim, So Young, Thomas, Sapana R., Wardwell, Leslie, Johnson, Laura A., Emery, Caroline M., Stransky, Nicolas, Cogdill, Alexandria P., Barretina, Jordi, Caponigro, Giordano, Hieronymus, Haley, Murray, Ryan R., Salehi-Ashtiani, Kourosh, Hill, David E., Vidal, Marc, Zhao, Jean J., Yang, Xiaoping, Alkan, Ozan, Kim, Sungjoon, Harris, Jennifer L., Wilson, Christopher J., Myer, Vic E., Finan, Peter M., Root, David E., Roberts, Thomas M., Golub, Todd, Flaherty, Keith T., Dummer, Reinhard, Weber, Barbara, Sellers, William R., Schlegel, Robert, Wargo, Jennifer A., Hahn, William C., Garraway, Levi A.
Izdano 2010