Apoptosis and cancer drug targeting

по Sellers, William R., Fisher, David E.
Опубликовано 1999

Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure

по Pagliarini, Raymond, Shao, Wenlin, Sellers, William R
Опубликовано в: EMBO Rep (2015)

Ribociclib (LEE011): mechanism of action and clinical impact of this selective cyclin-dependent kinase 4/6 inhibitor in various solid tumors

по Tripathy, Debu, Bardia, Aditya, Sellers, William R.
Опубликовано в: Clin Cancer Res (2017)

Big Data Approaches for Modeling Response and Resistance to Cancer Drugs

по Jiang, Peng, Sellers, William R., Liu, X. Shirley
Опубликовано в: Annu Rev Biomed Data Sci (2018)

Phosphorylation of the PTEN Tail Regulates Protein Stability and Function

по Vazquez, Francisca, Ramaswamy, Shivapriya, Nakamura, Noriaki, Sellers, William R.
Опубликовано 2000

Targeting pan-essential genes in cancer: challenges and opportunities

по Chang, Liang, Ruiz, Paloma, Ito, Takahiro, Sellers, William R.
Опубликовано в: Cancer Cell (2021)

Forkhead Transcription Factors Are Critical Effectors of Cell Death and Cell Cycle Arrest Downstream of PTEN

по Nakamura, Noriaki, Ramaswamy, Shivapriya, Vazquez, Francisca, Signoretti, Sabina, Loda, Massimo, Sellers, William R.
Опубликовано 2000

Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane

по Vazquez, Francisca, Matsuoka, Satomi, Sellers, William R., Yanagida, Toshio, Ueda, Masahiro, Devreotes, Peter N.
Опубликовано 2006

GEMINI: a variational Bayesian approach to identify genetic interactions from combinatorial CRISPR screens

по Zamanighomi, Mahdi, Jain, Sidharth S., Ito, Takahiro, Pal, Debjani, Daley, Timothy P., Sellers, William R.
Опубликовано в: Genome Biol (2019)

PTEN Nuclear Localization Is Regulated by Oxidative Stress and Mediates p53-Dependent Tumor Suppression

по Chang, Chun-Ju, Mulholland, David J., Valamehr, Bahram, Mosessian, Sherly, Sellers, William R., Wu, Hong
Опубликовано 2008

Regulation of G(1) progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

по Ramaswamy, Shivapriya, Nakamura, Noriaki, Vazquez, Francisca, Batt, David B., Perera, Sauni, Roberts, Thomas M., Sellers, William R.
Опубликовано 1999

Identification of prostate cancer modifier pathways using parental strain expression mapping

по Xu, Qing, Majumder, Pradip K., Ross, Kenneth, Shim, Yeonju, Golub, Todd R., Loda, Massimo, Sellers, William R.
Опубликовано 2007

SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines

по Demichelis, Francesca, Greulich, Heidi, Macoska, Jill A., Beroukhim, Rameen, Sellers, William R., Garraway, Levi, Rubin, Mark A.
Опубликовано 2008

Major copy proportion analysis of tumor samples using SNP arrays

по Li, Cheng, Beroukhim, Rameen, Weir, Barbara A, Winckler, Wendy, Garraway, Levi A, Sellers, William R, Meyerson, Matthew
Опубликовано 2008

PIK3CA mutation uncouples tumor growth and Cyclin D1 regulation from MEK/ERK and mutant KRAS signaling

по Halilovic, Ensar, She, Qing-Bai, Ye, Qing, Pagliarini, Raymond, Sellers, William R., Solit, David B., Rosen, Neal
Опубликовано 2010

A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens

по Hsieh, Andrew C., Bo, Ronghai, Manola, Judith, Vazquez, Francisca, Bare, Olivia, Khvorova, Anastasia, Scaringe, Stephen, Sellers, William R.
Опубликовано 2004

Allele-Specific Amplification in Cancer Revealed by SNP Array Analysis

по LaFramboise, Thomas, Weir, Barbara A, Zhao, Xiaojun, Beroukhim, Rameen, Li, Cheng, Harrington, David, Sellers, William R, Meyerson, Matthew
Опубликовано 2005

p85 Associates with Unphosphorylated PTEN and the PTEN-Associated Complex

по Rabinovsky, Rosalia, Pochanard, Panisa, McNear, Chontelle, Brachmann, Saskia M., Duke-Cohan, Jonathan S., Garraway, Levi A., Sellers, William R.
Опубликовано 2009

Retinoblastoma Protein Contains a C-terminal Motif That Targets It for Phosphorylation by Cyclin-cdk Complexes

по Adams, Peter D., Li, Xiaotong, Sellers, William R., Baker, Kayla B., Leng, Xiaohong, Harper, J. Wade, Taya, Yoichi, Kaelin, William G.
Опубликовано 1999

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

по Sellers, William R., Novitch, Bennett G., Miyake, Satoshi, Heith, Agnieszka, Otterson, Gregory A., Kaye, Frederic J., Lassar, Andrew B., Kaelin, William G.
Опубликовано 1998