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Phosphorylation of the PTEN Tail Regulates Protein Stability and Function

The PTEN gene is a tumor suppressor localized in the frequently altered chromosomal region 10q23. The tumor suppressor function of the PTEN protein (PTEN) has been linked to its ability to dephosphorylate the lipid second-messenger phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,...

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Detalhes bibliográficos
Main Authors: Vazquez, Francisca, Ramaswamy, Shivapriya, Nakamura, Noriaki, Sellers, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85951/
https://ncbi.nlm.nih.gov/pubmed/10866658
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