Phosphorylation of the PTEN Tail Regulates Protein Stability and Function

The PTEN gene is a tumor suppressor localized in the frequently altered chromosomal region 10q23. The tumor suppressor function of the PTEN protein (PTEN) has been linked to its ability to dephosphorylate the lipid second-messenger phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,...

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Hlavní autoři: Vazquez, Francisca, Ramaswamy, Shivapriya, Nakamura, Noriaki, Sellers, William R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC85951/
https://ncbi.nlm.nih.gov/pubmed/10866658
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