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ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability
Rho kinases belong to a family of serine/threonine kinases whose role in recruitment and migration of inflammatory cells is poorly understood. We show that deficiency of ROCK1 results in increased recruitment and migration of macrophages and neutrophils in vitro and in vivo. Enhanced migration resul...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832812/ https://ncbi.nlm.nih.gov/pubmed/20008297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-237222 |
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