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Tumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functions

The recruitment and activation of neutrophils at infected tissues is essential for host defense against invading microorganisms. However, excessive neutrophil recruitment or activation can also damage the surrounding tissues and cause unwanted inflammation. Hence, the responsiveness of neutrophils n...

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Hlavní autoři: Subramanian, Kulandayan K., Jia, Yonghui, Zhu, Daocheng, Simms, Benjamin T., Jo, Hakryul, Hattori, Hidenori, You, Jian, Mizgerd, Joseph P., Luo, Hongbo R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874585/
https://ncbi.nlm.nih.gov/pubmed/17202315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-055319
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