Inositol 1,3,4,5-tetrakisphosphate negatively regulates chemoattractant-elicited PtdIns(3,4,5)P3 signaling in neutrophils

Many neutrophil functions are mediated by PtdIns(3,4,5)P3, an essential cellular signaling molecule that exerts its function by mediating protein translocation via binding to their pleckstrin homolog (PH)-domains. In mammalian cells, its activity was previously thought to be dependent solely upon co...

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Detalhes bibliográficos
Main Authors: Jia, Yonghui, Subramanian, Kulandayan K., Erneux, Christophe, Pouillon, Valerie, Hattori, Hidenori, Jo, Hakryul, You, Jian, Zhu, Daocheng, Schurmans, Stephane, Luo, Hongbo R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084373/
https://ncbi.nlm.nih.gov/pubmed/17825589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.07.016
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