Inositol 1,3,4,5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells

The contribution of the B isoform of inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase (or Itpkb) and inositol 1,3,4,5-tetrakisphosphate [Ins(1,3,4,5)P(4)], its reaction product, to B cell function and development remains unknown. Here, we show that mice deficient in Itpkb have defects in B cel...

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Dades bibliogràfiques
Autors principals: Maréchal, Yoann, Pesesse, Xavier, Jia, Yonghui, Pouillon, Valérie, Pérez-Morga, David, Daniel, Julien, Izui, Shozo, Cullen, Peter J., Leo, Oberdan, Luo, Hongbo R., Erneux, Christophe, Schurmans, Stéphane
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955816/
https://ncbi.nlm.nih.gov/pubmed/17709751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704312104
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