Inositol 1,3,4,5-tetrakisphosphate negatively regulates chemoattractant-elicited PtdIns(3,4,5)P3 signaling in neutrophils

Many neutrophil functions are mediated by PtdIns(3,4,5)P3, an essential cellular signaling molecule that exerts its function by mediating protein translocation via binding to their pleckstrin homolog (PH)-domains. In mammalian cells, its activity was previously thought to be dependent solely upon co...

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Главные авторы: Jia, Yonghui, Subramanian, Kulandayan K., Erneux, Christophe, Pouillon, Valerie, Hattori, Hidenori, Jo, Hakryul, You, Jian, Zhu, Daocheng, Schurmans, Stephane, Luo, Hongbo R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084373/
https://ncbi.nlm.nih.gov/pubmed/17825589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.07.016
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