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The NOXO1β PX domain preferentially targets PtdIns(4,5)P(2) and PtdIns(3,4,5)P(3)

NOXO1β is a cytosolic protein which, in conjunction with NOXA1, regulates generation of reactive oxygen species (ROS) by the Nox1 enzyme complex. NOXO1β is targeted to membranes through an N-terminal PX domain. We have used nuclear magnetic resonance spectroscopy to solve the structure of the NOXO1β...

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Autors principals: Davis, Nicole Y., McPhail, Linda C., Horita, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304020/
https://ncbi.nlm.nih.gov/pubmed/22342885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.01.058
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