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The NOXO1β PX domain preferentially targets PtdIns(4,5)P(2) and PtdIns(3,4,5)P(3)
NOXO1β is a cytosolic protein which, in conjunction with NOXA1, regulates generation of reactive oxygen species (ROS) by the Nox1 enzyme complex. NOXO1β is targeted to membranes through an N-terminal PX domain. We have used nuclear magnetic resonance spectroscopy to solve the structure of the NOXO1β...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3304020/ https://ncbi.nlm.nih.gov/pubmed/22342885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.01.058 |
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