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Regulation of p53 Function and Stability by Phosphorylation

The p53 tumor suppressor protein can be phosphorylated at several sites within the N- and C-terminal domains, and several protein kinases have been shown to phosphorylate p53 in vitro. In this study, we examined the activity of p53 proteins with combined mutations at all of the reported N-terminal p...

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Detalhes bibliográficos
Main Authors: Ashcroft, Margaret, Kubbutat, Michael H. G., Vousden, Karen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC83968/
https://ncbi.nlm.nih.gov/pubmed/10022862
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