Series Introduction: Taking aim at novel molecular targets in cancer therapy

Por Kaelin, William G.
Publicado em 1999

Choosing anticancer drug targets in the postgenomic era

Por Kaelin, William G.
Publicado em 1999

Synthetic lethality: a framework for the development of wiser cancer therapeutics

Por Kaelin, William G
Publicado em 2009

Use and Abuse of RNAi to Study Mammalian Gene Function: Molecular Biology

Por Kaelin, William G.
Publicado em 2012

Cancer and Altered Metabolism: Potential Importance of HIF and 2-Oxoglutarate-dependent Dioxygenases

Por Kaelin, William G.
Publicado em 2011

New cancer targets emerging from studies of the Von Hippel-Lindau tumor suppressor protein

Por Kaelin, William G.
Publicado no Ann N Y Acad Sci (2010)

The VHL Tumor Suppressor Gene: Insights into Oxygen Sensing and Cancer

Por KAELIN, WILLIAM G.
Publicado no Trans Am Clin Climatol Assoc (2017)

HIF hydroxylation and the mammalian oxygen-sensing pathway

Por Safran, Michal, Kaelin, William G.
Publicado em 2003

Good COP1 or bad COP1? In vivo veritas

Por Wei, Wenyi, Kaelin, William G.
Publicado em 2011

New Insights into the Biology of Renal Cell Carcinoma

Por Li, Lianjie, Kaelin, William G.
Publicado em 2011

The VHL/HIF Axis in Clear Cell Renal Carcinoma

Por Shen, Chuan, Kaelin, William G.
Publicado em 2012

The EGLN-HIF O(2) Sensing System: Multiple Inputs and Feedbacks

Por Ivan, Mircea, Kaelin, William G.
Publicado no Mol Cell (2017)

Differential Control of Transcription by DNA-bound Cyclins

Por Kim, Tae-You, Kaelin, William G.
Publicado em 2001

What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer

Por Losman, Julie-Aurore, Kaelin, William G.
Publicado em 2013

Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss

Por Minamishima, Yoji Andrew, Kaelin, William G.
Publicado em 2010

pVHL(19) is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation

Por Iliopoulos, Othon, Ohh, Michael, Kaelin, William G.
Publicado em 1998

Influence of Metabolism on Epigenetics and Disease

Por Kaelin, William G., McKnight, Steven L.
Publicado em 2013

Inhibition of HIF2α Is Sufficient to Suppress pVHL-Defective Tumor Growth

Por Kondo, Keiichi, Kim, William Y, Lechpammer, Mirna, Kaelin, William G
Publicado em 2003

The Hypoxia-Inducible Factor 2α N-Terminal and C-Terminal Transactivation Domains Cooperate To Promote Renal Tumorigenesis In Vivo

Por Yan, Qin, Bartz, Steven, Mao, Mao, Li, Lianjie, Kaelin, William G.
Publicado em 2007

Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL(−/−) clear cell renal carcinoma

Por Gao, Wenhua, Li, Wei, Xiao, Tengfei, Liu, Xiaole Shirley, Kaelin, William G.
Publicado no Proc Natl Acad Sci U S A (2017)