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The VHL Tumor Suppressor Gene: Insights into Oxygen Sensing and Cancer

Mammalian cells sense changes in oxygen and transduce that information into adaptive changes in gene expression using a conserved pathway that converges on the heterodimeric transcription factor called hypoxia-inducible factor (HIF), which contains a labile alpha subunit and a stable beta subunit. I...

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Bibliografski detalji
Izdano u:Trans Am Clin Climatol Assoc
Glavni autor: KAELIN, WILLIAM G.
Format: Artigo
Jezik:Inglês
Izdano: American Clinical and Climatological Association 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525432/
https://ncbi.nlm.nih.gov/pubmed/28790514
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