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The VHL Tumor Suppressor Gene: Insights into Oxygen Sensing and Cancer
Mammalian cells sense changes in oxygen and transduce that information into adaptive changes in gene expression using a conserved pathway that converges on the heterodimeric transcription factor called hypoxia-inducible factor (HIF), which contains a labile alpha subunit and a stable beta subunit. I...
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| Veröffentlicht in: | Trans Am Clin Climatol Assoc |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Clinical and Climatological Association
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5525432/ https://ncbi.nlm.nih.gov/pubmed/28790514 |
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