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The VHL Tumor Suppressor Gene: Insights into Oxygen Sensing and Cancer

Mammalian cells sense changes in oxygen and transduce that information into adaptive changes in gene expression using a conserved pathway that converges on the heterodimeric transcription factor called hypoxia-inducible factor (HIF), which contains a labile alpha subunit and a stable beta subunit. I...

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Detaylı Bibliyografya
Yayımlandı:Trans Am Clin Climatol Assoc
Yazar: KAELIN, WILLIAM G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Clinical and Climatological Association 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525432/
https://ncbi.nlm.nih.gov/pubmed/28790514
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