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The VHL/HIF Axis in Clear Cell Renal Carcinoma
Inactivation of the VHL tumor suppressor protein (pVHL) is a common event in clear cell renal carcinoma, which is the most common form of kidney cancer. pVHL performs many functions, including serving as the substrate recognition module of an ubiquitin ligase complex that targets the alpha subunits...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663044/ https://ncbi.nlm.nih.gov/pubmed/22705278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2012.06.001 |
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