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The VHL/HIF Axis in Clear Cell Renal Carcinoma

Inactivation of the VHL tumor suppressor protein (pVHL) is a common event in clear cell renal carcinoma, which is the most common form of kidney cancer. pVHL performs many functions, including serving as the substrate recognition module of an ubiquitin ligase complex that targets the alpha subunits...

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Hlavní autoři: Shen, Chuan, Kaelin, William G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663044/
https://ncbi.nlm.nih.gov/pubmed/22705278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2012.06.001
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