What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer

Por Losman, Julie-Aurore, Kaelin, William G.
Publicado em 2013

(R)-2-Hydroxyglutarate is Sufficient to Promote Leukemogenesis and its Effects are Reversible

Por Losman, Julie-Aurore, Looper, Ryan, Koivunen, Peppi, Lee, Sungwoo, Schneider, Rebekka K., McMahon, Christine, Cowley, Glenn, Root, David, Ebert, Benjamin L., Kaelin, William G.
Publicado em 2013

Mutant calreticulin requires both its mutant C-terminus and the thrombopoietin receptor for oncogenic transformation

Por Elf, Shannon, Abdelfattah, Nouran S., Chen, Edwin, Perales-Patón, Javier, Rosen, Emily A., Ko, Amy, Peisker, Fabian, Florescu, Natalie, Giannini, Silvia, Wolach, Ofir, Morgan, Elizabeth A., Tothova, Zuzana, Losman, Julie-Aurore, Schneider, Rebekka K., Al-Shahrour, Fatima, Mullally, Ann
Publicado no Cancer Discov (2016)