Mouse models of myeloproliferative neoplasms: JAK of all grades

Por Li, Juan, Kent, David G., Chen, Edwin, Green, Anthony R.
Publicado em 2011

Smoking Among Chinese Americans: Behavior, Knowledge, and Beliefs

Por Yu, Elena S. H., Chen, Edwin H., Kim, Katherine K., Abdulrahim, Sawsan
Publicado em 2002

Risk factors for overweight in five- to six-year-old Hispanic-American children: A pilot study

Por Ariza, Adolfo J., Chen, Edwin H., Binns, Helen J., Christoffel, Katherine Kaufer
Publicado em 2004

Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175

Por Chen, Edwin, Paing, May M., Salinas, Nichole, Sim, B. Kim Lee, Tolia, Niraj H.
Publicado em 2013

Structural Analysis of the Synthetic Duffy Binding Protein (DBP) Antigen DEKnull Relevant for Plasmodium vivax Malaria Vaccine Design

Por Chen, Edwin, Salinas, Nichole D., Ntumngia, Francis B., Adams, John H., Tolia, Niraj H.
Publicado no PLoS Negl Trop Dis (2015)

Clonal analyses reveal associations of JAK2V617F homozygosity with hematologic features, age and gender in polycythemia vera and essential thrombocythemia

Por Godfrey, Anna L., Chen, Edwin, Pagano, Francesca, Silber, Yvonne, Campbell, Peter J., Green, Anthony R.
Publicado em 2013

Ectopic TLX1 Expression Accelerates Malignancies in Mice Deficient in DNA-PK

Por Krutikov, Konstantin, Zheng, Yanzhen, Chesney, Alden, Huang, Xiaoyong, Vaags, Andrea K., Evdokimova, Valentina, Hough, Margaret R., Chen, Edwin
Publicado em 2014

Phosphorylation of HOX11/TLX1 on Threonine-247 during mitosis modulates expression of cyclin B1

Por Chen, Edwin, Huang, Xiaoyong, Zheng, Yanzhen, Li, You-Jun, Chesney, Alden, Ben-David, Yaacov, Yang, Eric, Hough, Margaret R
Publicado em 2010

Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein

Por Chen, Edwin, Salinas, Nichole D., Huang, Yining, Ntumngia, Francis, Plasencia, Manolo D., Gross, Michael L., Adams, John H., Tolia, Niraj Harish
Publicado no Proc Natl Acad Sci U S A (2016)

Urinary p-nitrophenol as a biomarker of household exposure to methyl parathion.

Por Hryhorczuk, Daniel O, Moomey, Mike, Burton, Ann, Runkle, Ken, Chen, Edwin, Saxer, Tiffanie, Slightom, Jennifer, Dimos, John, McCann, Ken, Barr, Dana
Publicado em 2002

Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms

Por Chen, Edwin, Schneider, Rebekka K., Breyfogle, Lawrence J., Rosen, Emily A., Poveromo, Luke, Elf, Shannon, Ko, Amy, Brumme, Kristina, Levine, Ross, Ebert, Benjamin L., Mullally, Ann
Publicado no Blood (2015)

ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling

Por Wood, Andrew D., Chen, Edwin, Donaldson, Ian J., Hattangadi, Shilpa, Burke, Karly A., Dawson, Mark A., Miranda-Saavedra, Diego, Lodish, Harvey F., Green, Anthony R., Göttgens, Berthold
Publicado em 2009

RECQL5 suppresses oncogenic JAK2-induced replication stress and genomic instability

Por Chen, Edwin, Ahn, Jong Sook, Sykes, David B., Breyfogle, Lawrence J., Godfrey, Anna L., Nangalia, Jyoti, Ko, Amy, DeAngelo, Daniel J., Green, Anthony R., Mullally, Ann
Publicado no Cell Rep (2015)

Distinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signaling

Por Chen, Edwin, Beer, Philip A, Godfrey, Anna L, Ortmann, Christina A, Li, Juan, Costa-Pereira, Ana P., Ingle, Catherine E, Dermitzakis, Emmanouil T, Campbell, Peter J, Green, Anthony R.
Publicado em 2010

JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response

Por Chen, Edwin, Ahn, Jong Sook, Massie, Charlie E., Clynes, David, Godfrey, Anna L., Li, Juan, Park, Hyun Jung, Nangalia, Jyoti, Silber, Yvonne, Mullally, Ann, Gibbons, Richard J., Green, Anthony R.
Publicado em 2014

Benzoquinone ansamycin 17AAG binds to mitochondrial voltage-dependent anion channel and inhibits cell invasion

Por Xie, Qian, Wondergem, Robert, Shen, Yuehai, Cavey, Greg, Ke, Jiyuan, Thompson, Ryan, Bradley, Robert, Daugherty-Holtrop, Jennifer, Xu, Yong, Chen, Edwin, Omar, Hanan, Rosen, Neal, Wenkert, David, Xu, H. Eric, Vande Woude, George F.
Publicado em 2011

Mutant calreticulin requires both its mutant C-terminus and the thrombopoietin receptor for oncogenic transformation

Por Elf, Shannon, Abdelfattah, Nouran S., Chen, Edwin, Perales-Patón, Javier, Rosen, Emily A., Ko, Amy, Peisker, Fabian, Florescu, Natalie, Giannini, Silvia, Wolach, Ofir, Morgan, Elizabeth A., Tothova, Zuzana, Losman, Julie-Aurore, Schneider, Rebekka K., Al-Shahrour, Fatima, Mullally, Ann
Publicado no Cancer Discov (2016)

STAT1 activation in association with JAK2 exon 12 mutations

Por Godfrey, Anna L., Chen, Edwin, Massie, Charles E., Silber, Yvonne, Pagano, Francesca, Bellosillo, Beatriz, Guglielmelli, Paola, Harrison, Claire N., Reilly, John T., Stegelmann, Frank, Bijou, Fontanet, Lippert, Eric, Boiron, Jean-Michel, Döhner, Konstanze, Vannucchi, Alessandro M., Besses, Carlos, Green, Anthony R.
Publicado no Haematologica (2016)

JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia

Por Li, Juan, Spensberger, Dominik, Ahn, Jong Sook, Anand, Shubha, Beer, Philip A., Ghevaert, Cedric, Chen, Edwin, Forrai, Ariel, Scott, Linda M., Ferreira, Rita, Campbell, Peter J., Watson, Steve P., Liu, Pentao, Erber, Wendy N., Huntly, Brian J. P., Ottersbach, Katrin, Green, Anthony R.
Publicado em 2010

JAK2V617F homozygosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant homozygous subclone

Por Godfrey, Anna L., Chen, Edwin, Pagano, Francesca, Ortmann, Christina A., Silber, Yvonne, Bellosillo, Beatriz, Guglielmelli, Paola, Harrison, Claire N., Reilly, John T., Stegelmann, Frank, Bijou, Fontanet, Lippert, Eric, McMullin, Mary F., Boiron, Jean-Michel, Döhner, Konstanze, Vannucchi, Alessandro M., Besses, Carlos, Campbell, Peter J., Green, Anthony R.
Publicado em 2012