Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein

Plasmodium vivax Duffy Binding Protein (PvDBP) is the most promising vaccine candidate for P. vivax malaria. The polymorphic nature of PvDBP induces strain-specific immune responses, however, and the epitopes of broadly neutralizing antibodies are unknown. These features hamper the rational design o...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Chen, Edwin, Salinas, Nichole D., Huang, Yining, Ntumngia, Francis, Plasencia, Manolo D., Gross, Michael L., Adams, John H., Tolia, Niraj Harish
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896725/
https://ncbi.nlm.nih.gov/pubmed/27194724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600488113
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