A quantitative assay for binding and inhibition of Plasmodium falciparum Erythrocyte Binding Antigen 175 reveals high affinity binding depends on both DBL domains

di Salinas, Nichole D., Tolia, Niraj H.
Pubblicazione 2013

Red cell receptors as access points for malaria infection

di Salinas, Nichole D., Tolia, Niraj H.
Pubblicato in Curr Opin Hematol (2016)

Critical Glycosylated Residues in Exon Three of Erythrocyte Glycophorin A Engage Plasmodium falciparum EBA-175 and Define Receptor Specificity

di Salinas, Nichole D., Paing, May M., Tolia, Niraj H.
Pubblicazione 2014

Native Mass Spectrometry, Ion mobility, and Collision-Induced Unfolding Categorize Malaria Antigen/Antibody Binding

di Huang, Yining, Salinas, Nichole D., Chen, Edwin, Tolia, Niraj H., Gross, Michael L.
Pubblicato in J Am Soc Mass Spectrom (2017)

Moderately Neutralizing Epitopes in Nonfunctional Regions Dominate the Antibody Response to Plasmodium falciparum EBA-140

di Salinas, Nichole D., Paing, May M., Adhikari, Jagat, Gross, Michael L., Tolia, Niraj
Pubblicato in Infect Immun (2019)

Structural Analysis of the Synthetic Duffy Binding Protein (DBP) Antigen DEKnull Relevant for Plasmodium vivax Malaria Vaccine Design

di Chen, Edwin, Salinas, Nichole D., Ntumngia, Francis B., Adams, John H., Tolia, Niraj H.
Pubblicato in PLoS Negl Trop Dis (2015)

The structure of Acinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone–substrate interaction

di Urusova, Darya V., Kinsella, Rachel L., Salinas, Nichole D., Haurat, M. Florencia, Feldman, Mario F., Tolia, Niraj H.
Pubblicato in J Biol Chem (2019)

Shed EBA-175 mediates red blood cell clustering that enhances malaria parasite growth and enables immune evasion

di Paing, May M, Salinas, Nichole D, Adams, Yvonne, Oksman, Anna, Jensen, Anja TR, Goldberg, Daniel E, Tolia, Niraj H
Pubblicato in eLife (2018)

Defining the interaction of the protease CpaA with its type II secretion chaperone CpaB and its contribution to virulence in Acinetobacter species

di Kinsella, Rachel L., Lopez, Juvenal, Palmer, Lauren D., Salinas, Nichole D., Skaar, Eric P., Tolia, Niraj H., Feldman, Mario F.
Pubblicato in J Biol Chem (2017)

Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein

di Chen, Edwin, Salinas, Nichole D., Huang, Yining, Ntumngia, Francis, Plasencia, Manolo D., Gross, Michael L., Adams, John H., Tolia, Niraj Harish
Pubblicato in Proc Natl Acad Sci U S A (2016)

Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response

di Dickey, Thayne H., Tang, Wai Kwan, Butler, Brandi, Ouahes, Tarik, Orr-Gonzalez, Sachy, Salinas, Nichole D., Lambert, Lynn E., Tolia, Niraj H.
Pubblicato in bioRxiv (2021)

DARC extracellular domain remodeling in maturating reticulocytes explains Plasmodium vivax tropism

di Ovchynnikova, Elina, Aglialoro, Francesca, Bentlage, Arthur E. H., Vidarsson, Gestur, Salinas, Nichole D., von Lindern, Marieke, Tolia, Niraj H., van den Akker, Emile
Pubblicato in Blood (2017)

Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

di Jimah, John R, Salinas, Nichole D, Sala-Rabanal, Monica, Jones, Nathaniel G, Sibley, L David, Nichols, Colin G, Schlesinger, Paul H, Tolia, Niraj H
Pubblicato in eLife (2016)

Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion

di Koch, Marion, Wright, Katherine E., Otto, Oliver, Herbig, Maik, Salinas, Nichole D., Tolia, Niraj H., Satchwell, Timothy J., Guck, Jochen, Brooks, Nicholas J., Baum, Jake
Pubblicato in Proc Natl Acad Sci U S A (2017)

Structural basis for neutralization of P. vivax by naturally-acquired human antibodies that target DBP

di Urusova, Darya, Carias, Lenore, Huang, Yining, Nicolete, Vanessa C., Popovici, Jean, Roesch, Camille, Salinas, Nichole D., Witkowski, Benoit, Ferreira, Marcelo U., Adams, John H., Gross, Michael L., King, Christopher L., Tolia, Niraj H.
Pubblicato in Nat Microbiol (2019)

Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion

di Sisquella, Xavier, Nebl, Thomas, Thompson, Jennifer K, Whitehead, Lachlan, Malpede, Brian M, Salinas, Nichole D, Rogers, Kelly, Tolia, Niraj H, Fleig, Andrea, O’Neill, Joseph, Tham, Wai-Hong, David Horgen, F, Cowman, Alan F
Pubblicato in eLife (2017)

Naturally Acquired Antibody Response to Malaria Transmission Blocking Vaccine Candidate Pvs230 Domain 1

di Tentokam, Bergeline C. Nguemwo, Amaratunga, Chanaki, Alani, Nada A. H., MacDonald, Nicholas J., Narum, David L., Salinas, Nichole D., Kwan, Jennifer L., Suon, Seila, Sreng, Sokunthea, Pereira, Dhelio Batista, Tolia, Niraj H., Fujiwara, Ricardo T., Bueno, Lilian L., Duffy, Patrick E., Coelho, Camila H.
Pubblicato in Front Immunol (2019)

A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes

di Coelho, Camila H., Tang, Wai Kwan, Burkhardt, Martin, Galson, Jacob D., Muratova, Olga, Salinas, Nichole D., Alves e Silva, Thiago Luiz, Reiter, Karine, MacDonald, Nicholas J., Nguyen, Vu, Herrera, Raul, Shimp, Richard, Narum, David L., Byrne-Steele, Miranda, Pan, Wenjing, Hou, Xiaohong, Brown, Brittany, Eisenhower, Mary, Han, Jian, Jenkins, Bethany J., Doritchamou, Justin Y. A., Smelkinson, Margery G., Vega-Rodríguez, Joel, Trück, Johannes, Taylor, Justin J., Sagara, Issaka, Healy, Sara A., Renn, Jonathan P., Tolia, Niraj H., Duffy, Patrick E.
Pubblicato in Nat Commun (2021)