Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

Apicomplexan parasites contain a conserved protein CelTOS that, in malaria parasites, is essential for traversal of cells within the mammalian host and arthropod vector. However, the molecular role of CelTOS is unknown because it lacks sequence similarity to proteins of known function. Here, we dete...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Jimah, John R, Salinas, Nichole D, Sala-Rabanal, Monica, Jones, Nathaniel G, Sibley, L David, Nichols, Colin G, Schlesinger, Paul H, Tolia, Niraj H
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132341/
https://ncbi.nlm.nih.gov/pubmed/27906127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20621
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