Getting in: The structural biology of malaria invasion

Por Kumar, Hirdesh, Tolia, Niraj H.
Publicado no PLoS Pathog (2019)

A quantitative assay for binding and inhibition of Plasmodium falciparum Erythrocyte Binding Antigen 175 reveals high affinity binding depends on both DBL domains

Por Salinas, Nichole D., Tolia, Niraj H.
Publicado em 2013

Malaria Adhesins: Structure and Function

Por Malpede, Brian M., Tolia, Niraj H.
Publicado em 2014

Multimeric Assembly of Host-Pathogen Adhesion Complexes Involved in Apicomplexan Invasion

Por Paing, May M., Tolia, Niraj H.
Publicado em 2014

Red cell receptors as access points for malaria infection

Por Salinas, Nichole D., Tolia, Niraj H.
Publicado no Curr Opin Hematol (2016)

Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC

Por Batchelor, Joseph D., Zahm, Jacob A., Tolia, Niraj H.
Publicado em 2011

Molecular Basis for Sialic Acid-dependent Receptor Recognition by the Plasmodium falciparum Invasion Protein Erythrocyte-binding Antigen-140/BAEBL

Por Malpede, Brian M., Lin, Daniel H., Tolia, Niraj H.
Publicado em 2013

Critical Glycosylated Residues in Exon Three of Erythrocyte Glycophorin A Engage Plasmodium falciparum EBA-175 and Define Receptor Specificity

Por Salinas, Nichole D., Paing, May M., Tolia, Niraj H.
Publicado em 2014

Liposome Disruption Assay to Examine Lytic Properties of Biomolecules

Por Jimah, John R., Schlesinger, Paul H., Tolia, Niraj H.
Publicado no Bio Protoc (2017)

Membrane Lipid Screen to Identify Molecular Targets of Biomolecules

Por Jimah, John R., Schlesinger, Paul H., Tolia, Niraj H.
Publicado no Bio Protoc (2017)

Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1

Por Park, Jooyoung, Guggisberg, Ann M., Odom, Audrey R., Tolia, Niraj H.
Publicado no Acta Crystallogr D Biol Crystallogr (2015)

Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion

Por Lin, Daniel H., Malpede, Brian M., Batchelor, Joseph D., Tolia, Niraj H.
Publicado em 2012

Crystal structure of P. falciparum Cpn60 bound to ATP reveals an open dynamic conformation before substrate binding

Por Nguyen, Brian, Ma, Rui, Tang, Wai Kwan, Shi, Dashuang, Tolia, Niraj H.
Publicado no Sci Rep (2021)

Native Mass Spectrometry, Ion mobility, and Collision-Induced Unfolding Categorize Malaria Antigen/Antibody Binding

Por Huang, Yining, Salinas, Nichole D., Chen, Edwin, Tolia, Niraj H., Gross, Michael L.
Publicado no J Am Soc Mass Spectrom (2017)

Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175

Por Chen, Edwin, Paing, May M., Salinas, Nichole, Sim, B. Kim Lee, Tolia, Niraj H.
Publicado em 2013

Structural Analysis of the Synthetic Duffy Binding Protein (DBP) Antigen DEKnull Relevant for Plasmodium vivax Malaria Vaccine Design

Por Chen, Edwin, Salinas, Nichole D., Ntumngia, Francis B., Adams, John H., Tolia, Niraj H.
Publicado no PLoS Negl Trop Dis (2015)

Exploring the “minimal” structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering

Por Zhu, Jian, Muia, Joshua, Gupta, Garima, Westfield, Lisa A., Vanhoorelbeke, Karen, Tolia, Niraj H., Sadler, J. Evan
Publicado no Blood (2019)

Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC

Por Batchelor, Joseph D., Malpede, Brian M., Omattage, Natalie S., DeKoster, Gregory T., Henzler-Wildman, Katherine A., Tolia, Niraj H.
Publicado em 2014

Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii

Por Behnke, Michael S., Khan, Asis, Lauron, Elvin J., Jimah, John R., Wang, Qiuling, Tolia, Niraj H., Sibley, L. David
Publicado no PLoS Genet (2015)

The structure of Acinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone–substrate interaction

Por Urusova, Darya V., Kinsella, Rachel L., Salinas, Nichole D., Haurat, M. Florencia, Feldman, Mario F., Tolia, Niraj H.
Publicado no J Biol Chem (2019)