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Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii

Toxoplasma gondii has evolved a number of strategies to evade immune responses in its many hosts. Previous genetic mapping of crosses between clonal type 1, 2, and 3 strains of T. gondii, which are prevalent in Europe and North America, identified two rhoptry proteins, ROP5 and ROP18, that function...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Behnke, Michael S., Khan, Asis, Lauron, Elvin J., Jimah, John R., Wang, Qiuling, Tolia, Niraj H., Sibley, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546408/
https://ncbi.nlm.nih.gov/pubmed/26291965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005434
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