Plasmodium falciparum Resistance to Artemisinin Derivatives and Piperaquine: A Major Challenge for Malaria Elimination in Cambodia

per Duru, Valentine, Witkowski, Benoit, Ménard, Didier
Publicat a Am J Trop Med Hyg (2016)

Primaquine for Plasmodium vivax radical cure: What we do not know and why it matters

per Popovici, Jean, Tebben, Kieran, Witkowski, Benoit, Serre, David
Publicat a Int J Parasitol Drugs Drug Resist (2021)

Correlation between Plasmodium yoelii nigeriensis Susceptibility to Artemisinin and Alkylation of Heme by the Drug

per Robert, Anne, Claparols, Catherine, Witkowski, Benoit, Benoit-Vical, Françoise
Publicat 2013

Artemisinin resistance in Plasmodium falciparum

per Amaratunga, Chanaki, Witkowski, Benoit, Khim, Nimol, Menard, Didier, Fairhurst, Rick M.
Publicat a Lancet Infect Dis (2014)

Impact of the first-line treatment shift from dihydroartemisinin/piperaquine to artesunate/mefloquine on Plasmodium vivax drug susceptibility in Cambodia

per Roesch, Camille, Mairet-Khedim, Mélissa, Kim, Saorin, Lek, Dysoley, Popovici, Jean, Witkowski, Benoit
Publicat a J Antimicrob Chemother (2020)

Implication of Glutathione in the In Vitro Antiplasmodial Mechanism of Action of Ellagic Acid

per Njomnang Soh, Patrice, Witkowski, Benoit, Gales, Amandine, Huyghe, Eric, Berry, Antoine, Pipy, Bernard, Benoit-Vical, Françoise
Publicat 2012

Plasmodium falciparum Founder Populations in Western Cambodia Have Reduced Artemisinin Sensitivity In Vitro

per Amaratunga, Chanaki, Witkowski, Benoit, Dek, Dalin, Try, Vorleak, Khim, Nimol, Miotto, Olivo, Ménard, Didier, Fairhurst, Rick M.
Publicat 2014

Increased Tolerance to Artemisinin in Plasmodium falciparum Is Mediated by a Quiescence Mechanism

per Witkowski, Benoit, Lelièvre, Joel, López Barragán, María José, Laurent, Victor, Su, Xin-zhuan, Berry, Antoine, Benoit-Vical, Françoise
Publicat 2010

In Vitro and In Vivo Properties of Ellagic Acid in Malaria Treatment

per Soh, Patrice Njomnang, Witkowski, Benoît, Olagnier, David, Nicolau, Marie-Laure, Garcia-Alvarez, Maria-Concepcion, Berry, Antoine, Benoit-Vical, Françoise
Publicat 2009

Global analysis of Plasmodium falciparum Na(+)/H(+) exchanger (pfnhe-1) allele polymorphism and its usefulness as a marker of in vitro resistance to quinine

per Ménard, Didier, Andriantsoanirina, Valérie, Khim, Nimol, Ratsimbasoa, Arsène, Witkowski, Benoit, Benedet, Christophe, Canier, Lydie, Mercereau-Puijalon, Odile, Durand, Rémy
Publicat 2012

Plasmodium falciparum Na(+)/H(+) Exchanger (pfnhe-1) Genetic Polymorphism in Indian Ocean Malaria-Endemic Areas

per Andriantsoanirina, Valérie, Khim, Nimol, Ratsimbasoa, Arsene, Witkowski, Benoit, Benedet, Christophe, Canier, Lydie, Bouchier, Christiane, Tichit, Magali, Durand, Rémy, Ménard, Didier
Publicat 2013

Performance of Ultrasensitive Rapid Diagnostic Tests for Detecting Asymptomatic Plasmodium falciparum

per Yeung, Shunmay, McGregor, David, James, Nicola, Kheang, Soy Ty, Kim, Saorin, Khim, Nimol, Ly, Po, Sovannaroth, Siv, Witkowski, Benoit
Publicat a Am J Trop Med Hyg (2020)

Efficacy and Safety of Pyronaridine-Artesunate plus Single-Dose Primaquine for Treatment of Uncomplicated Plasmodium falciparum Malaria in Eastern Cambodia

per Leang, Rithea, Mairet-Khedim, Melissa, Chea, Huch, Huy, Rekol, Khim, Nimol, Mey Bouth, Denis, Dorina Bustos, Maria, Ringwald, Pascal, Witkowski, Benoit
Publicat a Antimicrob Agents Chemother (2019)

Efficacy and Safety of Pyronaridine-Artesunate plus Single-Dose Primaquine for the Treatment of Malaria in Western Cambodia

per Leang, Rithea, Khim, Nimol, Chea, Huch, Huy, Rekol, Mairet-Khedim, Melissa, Mey Bouth, Denis, Dorina Bustos, Maria, Ringwald, Pascal, Witkowski, Benoit
Publicat a Antimicrob Agents Chemother (2019)

Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity

per Popovici, Jean, Roesch, Camille, Carias, Lenore L., Khim, Nimol, Kim, Saorin, Vantaux, Amelie, Mueller, Ivo, Chitnis, Chetan E., King, Christopher L., Witkowski, Benoit
Publicat a Nat Commun (2020)

Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3

per Posfai, Dora, Maher, Steven P., Roesch, Camille, Vantaux, Amélie, Sylvester, Kayla, Péneau, Julie, Popovici, Jean, Kyle, Dennis E., Witkowski, Benoît, Derbyshire, Emily R.
Publicat a Cell Chem Biol (2020)

Plasmodium falciparum Isolates with Increased pfmdr1 Copy Number Circulate in West Africa

per Witkowski, Benoit, Nicolau, Marie-Laure, Soh, Patrice Njomnang, Iriart, Xavier, Menard, Sandie, Alvarez, Muriel, Marchou, Bruno, Magnaval, Jean-François, Benoit-Vical, Françoise, Berry, Antoine
Publicat 2010

pfmdr1 Amplification Associated with Clinical Resistance to Mefloquine in West Africa: Implications for Efficacy of Artemisinin Combination Therapies

per Witkowski, Benoit, Iriart, Xavier, Soh, Patrice Njomnang, Menard, Sandie, Alvarez, Muriel, Naneix-Laroche, Veronique, Marchou, Bruno, Magnaval, Jean-François, Benoit-Vical, Françoise, Berry, Antoine
Publicat 2010

Evidence for the Contribution of the Hemozoin Synthesis Pathway of the Murine Plasmodium yoelii to the Resistance to Artemisinin-Related Drugs

per Witkowski, Benoit, Lelièvre, Joel, Nicolau-Travers, Marie-Laure, Iriart, Xavier, Njomnang Soh, Patrice, Bousejra-ElGarah, Fatima, Meunier, Bernard, Berry, Antoine, Benoit-Vical, Françoise
Publicat 2012

DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites

per Nardella, Flore, Halby, Ludovic, Hammam, Elie, Erdmann, Diane, Cadet-Daniel, Véronique, Peronet, Roger, Ménard, Didier, Witkowski, Benoit, Mecheri, Salah, Scherf, Artur, Arimondo, Paola B.
Publicat a ACS Cent Sci (2019)