Plasmodium falciparum Resistance to Artemisinin Derivatives and Piperaquine: A Major Challenge for Malaria Elimination in Cambodia

por Duru, Valentine, Witkowski, Benoit, Ménard, Didier
Publicado en Am J Trop Med Hyg (2016)

Primaquine for Plasmodium vivax radical cure: What we do not know and why it matters

por Popovici, Jean, Tebben, Kieran, Witkowski, Benoit, Serre, David
Publicado en Int J Parasitol Drugs Drug Resist (2021)

Correlation between Plasmodium yoelii nigeriensis Susceptibility to Artemisinin and Alkylation of Heme by the Drug

por Robert, Anne, Claparols, Catherine, Witkowski, Benoit, Benoit-Vical, Françoise
Publicado 2013

Artemisinin resistance in Plasmodium falciparum

por Amaratunga, Chanaki, Witkowski, Benoit, Khim, Nimol, Menard, Didier, Fairhurst, Rick M.
Publicado en Lancet Infect Dis (2014)

Impact of the first-line treatment shift from dihydroartemisinin/piperaquine to artesunate/mefloquine on Plasmodium vivax drug susceptibility in Cambodia

por Roesch, Camille, Mairet-Khedim, Mélissa, Kim, Saorin, Lek, Dysoley, Popovici, Jean, Witkowski, Benoit
Publicado en J Antimicrob Chemother (2020)

Implication of Glutathione in the In Vitro Antiplasmodial Mechanism of Action of Ellagic Acid

por Njomnang Soh, Patrice, Witkowski, Benoit, Gales, Amandine, Huyghe, Eric, Berry, Antoine, Pipy, Bernard, Benoit-Vical, Françoise
Publicado 2012

Plasmodium falciparum Founder Populations in Western Cambodia Have Reduced Artemisinin Sensitivity In Vitro

por Amaratunga, Chanaki, Witkowski, Benoit, Dek, Dalin, Try, Vorleak, Khim, Nimol, Miotto, Olivo, Ménard, Didier, Fairhurst, Rick M.
Publicado 2014

Increased Tolerance to Artemisinin in Plasmodium falciparum Is Mediated by a Quiescence Mechanism

por Witkowski, Benoit, Lelièvre, Joel, López Barragán, María José, Laurent, Victor, Su, Xin-zhuan, Berry, Antoine, Benoit-Vical, Françoise
Publicado 2010

In Vitro and In Vivo Properties of Ellagic Acid in Malaria Treatment

por Soh, Patrice Njomnang, Witkowski, Benoît, Olagnier, David, Nicolau, Marie-Laure, Garcia-Alvarez, Maria-Concepcion, Berry, Antoine, Benoit-Vical, Françoise
Publicado 2009

Global analysis of Plasmodium falciparum Na(+)/H(+) exchanger (pfnhe-1) allele polymorphism and its usefulness as a marker of in vitro resistance to quinine

por Ménard, Didier, Andriantsoanirina, Valérie, Khim, Nimol, Ratsimbasoa, Arsène, Witkowski, Benoit, Benedet, Christophe, Canier, Lydie, Mercereau-Puijalon, Odile, Durand, Rémy
Publicado 2012

Plasmodium falciparum Na(+)/H(+) Exchanger (pfnhe-1) Genetic Polymorphism in Indian Ocean Malaria-Endemic Areas

por Andriantsoanirina, Valérie, Khim, Nimol, Ratsimbasoa, Arsene, Witkowski, Benoit, Benedet, Christophe, Canier, Lydie, Bouchier, Christiane, Tichit, Magali, Durand, Rémy, Ménard, Didier
Publicado 2013

Performance of Ultrasensitive Rapid Diagnostic Tests for Detecting Asymptomatic Plasmodium falciparum

por Yeung, Shunmay, McGregor, David, James, Nicola, Kheang, Soy Ty, Kim, Saorin, Khim, Nimol, Ly, Po, Sovannaroth, Siv, Witkowski, Benoit
Publicado en Am J Trop Med Hyg (2020)

Efficacy and Safety of Pyronaridine-Artesunate plus Single-Dose Primaquine for Treatment of Uncomplicated Plasmodium falciparum Malaria in Eastern Cambodia

por Leang, Rithea, Mairet-Khedim, Melissa, Chea, Huch, Huy, Rekol, Khim, Nimol, Mey Bouth, Denis, Dorina Bustos, Maria, Ringwald, Pascal, Witkowski, Benoit
Publicado en Antimicrob Agents Chemother (2019)

Efficacy and Safety of Pyronaridine-Artesunate plus Single-Dose Primaquine for the Treatment of Malaria in Western Cambodia

por Leang, Rithea, Khim, Nimol, Chea, Huch, Huy, Rekol, Mairet-Khedim, Melissa, Mey Bouth, Denis, Dorina Bustos, Maria, Ringwald, Pascal, Witkowski, Benoit
Publicado en Antimicrob Agents Chemother (2019)

Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity

por Popovici, Jean, Roesch, Camille, Carias, Lenore L., Khim, Nimol, Kim, Saorin, Vantaux, Amelie, Mueller, Ivo, Chitnis, Chetan E., King, Christopher L., Witkowski, Benoit
Publicado en Nat Commun (2020)

Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3

por Posfai, Dora, Maher, Steven P., Roesch, Camille, Vantaux, Amélie, Sylvester, Kayla, Péneau, Julie, Popovici, Jean, Kyle, Dennis E., Witkowski, Benoît, Derbyshire, Emily R.
Publicado en Cell Chem Biol (2020)

Plasmodium falciparum Isolates with Increased pfmdr1 Copy Number Circulate in West Africa

por Witkowski, Benoit, Nicolau, Marie-Laure, Soh, Patrice Njomnang, Iriart, Xavier, Menard, Sandie, Alvarez, Muriel, Marchou, Bruno, Magnaval, Jean-François, Benoit-Vical, Françoise, Berry, Antoine
Publicado 2010

pfmdr1 Amplification Associated with Clinical Resistance to Mefloquine in West Africa: Implications for Efficacy of Artemisinin Combination Therapies

por Witkowski, Benoit, Iriart, Xavier, Soh, Patrice Njomnang, Menard, Sandie, Alvarez, Muriel, Naneix-Laroche, Veronique, Marchou, Bruno, Magnaval, Jean-François, Benoit-Vical, Françoise, Berry, Antoine
Publicado 2010

Evidence for the Contribution of the Hemozoin Synthesis Pathway of the Murine Plasmodium yoelii to the Resistance to Artemisinin-Related Drugs

por Witkowski, Benoit, Lelièvre, Joel, Nicolau-Travers, Marie-Laure, Iriart, Xavier, Njomnang Soh, Patrice, Bousejra-ElGarah, Fatima, Meunier, Bernard, Berry, Antoine, Benoit-Vical, Françoise
Publicado 2012

DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites

por Nardella, Flore, Halby, Ludovic, Hammam, Elie, Erdmann, Diane, Cadet-Daniel, Véronique, Peronet, Roger, Ménard, Didier, Witkowski, Benoit, Mecheri, Salah, Scherf, Artur, Arimondo, Paola B.
Publicado en ACS Cent Sci (2019)