Efficacy and Safety of Pyronaridine-Artesunate plus Single-Dose Primaquine for the Treatment of Malaria in Western Cambodia

This single-arm trial (n = 104) in western Cambodia showed high efficacy for 3-day treatment with pyronaridine-artesunate plus single-dose primaquine in Plasmodium falciparum malaria. Day 42 PCR-adjusted adequate clinical and parasitological response (ACPR) was 98.3% (58/59) (95% confidence interval...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Leang, Rithea, Khim, Nimol, Chea, Huch, Huy, Rekol, Mairet-Khedim, Melissa, Mey Bouth, Denis, Dorina Bustos, Maria, Ringwald, Pascal, Witkowski, Benoit
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761550/
https://ncbi.nlm.nih.gov/pubmed/31358594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01273-19
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