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Correlation between Plasmodium yoelii nigeriensis Susceptibility to Artemisinin and Alkylation of Heme by the Drug

Evidence of artemisinin (ART) resistance in all of the Greater Mekong Region is currently of major concern. Understanding of the mechanisms of resistance developed by Plasmodium against artemisinin and its derivatives is urgently needed. We here demonstrated that ART was able to alkylate heme in mic...

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Hlavní autoři: Robert, Anne, Claparols, Catherine, Witkowski, Benoit, Benoit-Vical, Françoise
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719719/
https://ncbi.nlm.nih.gov/pubmed/23752508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01064-13
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