Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein

Plasmodium vivax Duffy Binding Protein (PvDBP) is the most promising vaccine candidate for P. vivax malaria. The polymorphic nature of PvDBP induces strain-specific immune responses, however, and the epitopes of broadly neutralizing antibodies are unknown. These features hamper the rational design o...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Chen, Edwin, Salinas, Nichole D., Huang, Yining, Ntumngia, Francis, Plasencia, Manolo D., Gross, Michael L., Adams, John H., Tolia, Niraj Harish
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896725/
https://ncbi.nlm.nih.gov/pubmed/27194724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600488113
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