Identification of an Immunogenic Broadly Inhibitory Surface Epitope of the Plasmodium vivax Duffy Binding Protein Ligand Domain

The Plasmodium vivax Duffy binding protein region II (DBPII) is a vital ligand for the parasite’s invasion of reticulocytes, thereby making this molecule an attractive vaccine candidate against vivax malaria. However, strain-specific immunity due to DBPII allelic variation in Bc epitopes may complic...

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Détails bibliographiques
Publié dans:mSphere
Auteurs principaux: George, Miriam T., Schloegel, Jesse L., Ntumngia, Francis B., Barnes, Samantha J., King, Christopher L., Casey, Joanne L., Foley, Michael, Adams, John H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520440/
https://ncbi.nlm.nih.gov/pubmed/31092602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00194-19
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