Clonal analyses reveal associations of JAK2V617F homozygosity with hematologic features, age and gender in polycythemia vera and essential thrombocythemia

Por Godfrey, Anna L., Chen, Edwin, Pagano, Francesca, Silber, Yvonne, Campbell, Peter J., Green, Anthony R.
Publicado em 2013

Nongenetic stochastic expansion of JAK2V617F-homozygous subclones in polycythemia vera?

Por Godfrey, Anna L., Nangalia, Jyoti, Baxter, E. Joanna, Massie, Charles E., Kent, David G., Papaemmanuil, Elli, Campbell, Peter J., Green, Anthony R.
Publicado no Blood (2014)

RECQL5 suppresses oncogenic JAK2-induced replication stress and genomic instability

Por Chen, Edwin, Ahn, Jong Sook, Sykes, David B., Breyfogle, Lawrence J., Godfrey, Anna L., Nangalia, Jyoti, Ko, Amy, DeAngelo, Daniel J., Green, Anthony R., Mullally, Ann
Publicado no Cell Rep (2015)

Distinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signaling

Por Chen, Edwin, Beer, Philip A, Godfrey, Anna L, Ortmann, Christina A, Li, Juan, Costa-Pereira, Ana P., Ingle, Catherine E, Dermitzakis, Emmanouil T, Campbell, Peter J, Green, Anthony R.
Publicado em 2010

JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response

Por Chen, Edwin, Ahn, Jong Sook, Massie, Charlie E., Clynes, David, Godfrey, Anna L., Li, Juan, Park, Hyun Jung, Nangalia, Jyoti, Silber, Yvonne, Mullally, Ann, Gibbons, Richard J., Green, Anthony R.
Publicado em 2014

DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype

Por Nangalia, Jyoti, Nice, Francesca L., Wedge, David C., Godfrey, Anna L, Grinfeld, Jacob, Thakker, Clare, Massie, Charlie E., Baxter, Joanna, Sewell, David, Silber, Yvonne, Campbell, Peter J., Green, Anthony R.
Publicado no Haematologica (2015)

STAT1 activation in association with JAK2 exon 12 mutations

Por Godfrey, Anna L., Chen, Edwin, Massie, Charles E., Silber, Yvonne, Pagano, Francesca, Bellosillo, Beatriz, Guglielmelli, Paola, Harrison, Claire N., Reilly, John T., Stegelmann, Frank, Bijou, Fontanet, Lippert, Eric, Boiron, Jean-Michel, Döhner, Konstanze, Vannucchi, Alessandro M., Besses, Carlos, Green, Anthony R.
Publicado no Haematologica (2016)

JAK2V617F homozygosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant homozygous subclone

Por Godfrey, Anna L., Chen, Edwin, Pagano, Francesca, Ortmann, Christina A., Silber, Yvonne, Bellosillo, Beatriz, Guglielmelli, Paola, Harrison, Claire N., Reilly, John T., Stegelmann, Frank, Bijou, Fontanet, Lippert, Eric, McMullin, Mary F., Boiron, Jean-Michel, Döhner, Konstanze, Vannucchi, Alessandro M., Besses, Carlos, Campbell, Peter J., Green, Anthony R.
Publicado em 2012

Effect of Mutation Order on Myeloproliferative Neoplasms

Por Ortmann, Christina A., Kent, David G., Nangalia, Jyoti, Silber, Yvonne, Wedge, David C., Grinfeld, Jacob, Baxter, E. Joanna, Massie, Charles E., Papaemmanuil, Elli, Menon, Suraj, Godfrey, Anna L., Dimitropoulou, Danai, Guglielmelli, Paola, Bellosillo, Beatriz, Besses, Carles, Döhner, Konstanze, Harrison, Claire N., Vassiliou, George S., Vannucchi, Alessandro, Campbell, Peter J., Green, Anthony R.
Publicado no N Engl J Med (2015)

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms

Por Malcovati, Luca, Papaemmanuil, Elli, Bowen, David T., Boultwood, Jacqueline, Della Porta, Matteo G., Pascutto, Cristiana, Travaglino, Erica, Groves, Michael J., Godfrey, Anna L., Ambaglio, Ilaria, Gallì, Anna, Da Vià, Matteo C., Conte, Simona, Tauro, Sudhir, Keenan, Norene, Hyslop, Ann, Hinton, Jonathan, Mudie, Laura J., Wainscoat, James S., Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J., Hellström-Lindberg, Eva, Cazzola, Mario
Publicado em 2011

Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

Por Tapper, William, Jones, Amy V., Kralovics, Robert, Harutyunyan, Ashot S., Zoi, Katerina, Leung, William, Godfrey, Anna L., Guglielmelli, Paola, Callaway, Alison, Ward, Daniel, Aranaz, Paula, White, Helen E., Waghorn, Katherine, Lin, Feng, Chase, Andrew, Joanna Baxter, E., Maclean, Cathy, Nangalia, Jyoti, Chen, Edwin, Evans, Paul, Short, Michael, Jack, Andrew, Wallis, Louise, Oscier, David, Duncombe, Andrew S., Schuh, Anna, Mead, Adam J., Griffiths, Michael, Ewing, Joanne, Gale, Rosemary E., Schnittger, Susanne, Haferlach, Torsten, Stegelmann, Frank, Döhner, Konstanze, Grallert, Harald, Strauch, Konstantin, Tanaka, Toshiko, Bandinelli, Stefania, Giannopoulos, Andreas, Pieri, Lisa, Mannarelli, Carmela, Gisslinger, Heinz, Barosi, Giovanni, Cazzola, Mario, Reiter, Andreas, Harrison, Claire, Campbell, Peter, Green, Anthony R., Vannucchi, Alessandro, Cross, Nicholas C.P.
Publicado no Nat Commun (2015)