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Mouse models of myeloproliferative neoplasms: JAK of all grades

In 2005, several groups identified a single gain-of-function point mutation in the JAK2 kinase that was present in the majority of patients with myeloproliferative neoplasms (MPNs). Since this discovery, much effort has been dedicated to understanding the molecular consequences of the JAK2V617F muta...

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Detalles Bibliográficos
Main Authors: Li, Juan, Kent, David G., Chen, Edwin, Green, Anthony R.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Limited 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097453/
https://ncbi.nlm.nih.gov/pubmed/21558064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.006817
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