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Update on JAK2 Inhibitors in Myeloproliferative Neoplasm

Since the discovery of mutant Janus Kinase 2 (JAK2), JAK2 V617F, in a major proportion of myeloproliferative neoplasm (MPN) patients, there has been a flurry of activity in the development of JAK2 inhibitors. Pan-JAK, predominantly JAK2 and off-target JAK2 inhibitors have been developed in the short...

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Detalhes bibliográficos
Main Authors: Chan, Daniel, Koren-Michowitz, Maya
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573400/
https://ncbi.nlm.nih.gov/pubmed/23556077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620711401646
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