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Therapy with JAK2 inhibitors for Myeloproliferative Neoplasms
The development of JAK2 inhibitors followed the discovery of activating mutation of JAK2 (JAK2V617F) in patients with classic Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPNs). It is now known that mutations activating the JAK-STAT pathway are ubiquitous in Ph-negative MPNs, and...
Tallennettuna:
| Julkaisussa: | Hematol Oncol Clin North Am |
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| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406395/ https://ncbi.nlm.nih.gov/pubmed/23009939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2012.07.008 |
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